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Perhaps the most impactful and root-cause way that you can influence your guts GLP-1 production is by balancing your microbiome
It is responsible for inactivating incretins, such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1)
GLP-1 medications are synthetic versions of this hormone, engineered to last much longer than the natural version which degrades within minutes
For context, metformin monotherapy typically reduces A1C by 1.0 to 1.5% in treatment-naive populations
Confocal microscopy analysis of RBCs from chronic arsenic-exposed rats gave evidence of Fas aggregation and DISC assembly in the cell membrane that culminated in caspase-8 and caspase-3 activation
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