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Machine learning models are being used to design permeation enhancerssmall molecules that temporarily open the tight junctions in the gut lining to let the peptide pass through
Using urinary hesperetin as a marker of dietary hesperidin, another group of researchers found those with the highest level of hesperidin intake had 32% lower risk of developing diabetes over 4.6 years compared to those with the lowest intake level (Sun 2015)
Recently, new medications have been approved by the Food and Drug Administration (FDA) for clinical use after years of rigorous trials in human subjects
Nature Communications paper
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