In my work as a clinician working in obesity medicine, I see GLP-1 and GIP-based therapies help patients do something that used to feel out of reach: achieve clinically meaningful weight loss while also improving blood pressure, blood sugar, cholesterol, sleep, mobility, and quality of life
Zepbound (tirzepatide) weekly injection dosing schedule The weekly dosing schedule of Zepboud is as follows: Weeks 1-4 (starting dose): 2.5 mg once weekly for the first 4 weeks Weeks 5-8: 5 mg once weekly Weeks 9-12: 7.5 mg once weekly Weeks 13-16 : If tolerated, increase to 10 mg once weekly Weeks 17-20: If the dosage needs to be escalated further, increase to 12.5 mg once weekly for 4 weeks Weeks 21 and onward : If the previous dose is ineffective, the next dose will be 15 mg once weekly
Weight loss and improved insulin sensitivity also play important roles
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While GLP-1 receptor agonists (GLP-1-RA) directly target GLP-1, GLP-1-independent effects are also possible with the use of DPP4 inhibitors (DPP4i)