In a retrospective study completed by Nadeem et al., it was shown that GLP-1 RAs are associated with an overall fourfold increase in the retention of gastric contents in both diabetic and non-diabetic patients ( p -value 0.8 mL/kg of gastric fluid content (measured from the aspiration/suction canister)
When the microbiome is disrupted, Candida shifts into an invasive form that penetrates the gut lining, releases toxic metabolites, and triggers a cascade of symptoms that can span every system in the body: fatigue, brain fog, recurrent infections, skin problems, and mood instability
This can significantly reduce the desire to eat between meals, supporting sustained weight loss efforts
Some symptoms may be brief and mild, while others may require evaluation by the prescribing provider
Journal of Endocrinology 179 , 447454, doi:10.1677/joe.0.1790447 (2003)