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Increased permeability for saccharides has been reported in patients with CD [137],[138], celiac disease [139], adverse reaction to food [140],[141], and in critically ill patients or patients undergoing major surgery [142],[143]

Cyanocobalamin has documented antiemetic properties, though the exact mechanism remains incompletely understood

The NHS schedule for treating B12 deficiency is a loading dose of 1mg hydroxocobalamin by intramuscular injection every two to three days for two weeks, then a maintenance dose every two to three months for life when the cause is non-dietary

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