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The goal is to help your biology better match your calendar

Whilst GLP-1 receptor agonists primarily work by enhancing insulin secretion rather than directly improving insulin sensitivity at the cellular level, the associated weight loss that often occurs with these medications can lead to secondary improvements in insulin resistance

Dividing the doses to optimize efficacy is advisable rather than taking a single large daily dose

and hypoglycemia

Efinopegdutide is another GLP-1R and GCGR dual agonist currently under clinical investigation, which is being explored in studies for patients with obesity, type 2 diabetes (T2D), and metabolically associated fatty liver disease/multiple acyl-CoA dehydrogenase deficiency syndrome (MASLD/MASH)