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The FDA classifies BPC-157 as a Category 2 bulk drug substance meaning its not FDA-approved for human use and has been flagged as potentially presenting safety risks in unregulated compounding

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Some users prefer longer cycles of 16 to 20 weeks followed by proportionally longer off periods

They also offer more controllable results, making them more ideal for precise enhancements like the lips, and PRF more suitable for broader areas, such as tear troughs