fda retatrutide Lilly, with new data, to seek approval of obesity drug Demand for Unapproved Weight-Loss Drug

The manufacturer Novo Nordisk has struggled to meet demand since 2022

14 The most common adverse effects associated with oral creatine include 14,16 Dehydration Diarrhea Gastrointestinal upset Muscle cramps Water retention leading to weight gain It is rare to experience severe adverse effects when taking creatine, however, the following may occur 14 Interstitial nephritis Renal insufficiency Rhabdomyolysis Venous thrombosis Prior to beginning creatine supplementation, individuals with the following conditions should avoid its use until first discussed with their physician: 16 Bipolar disease (may increase mania) Diabetes Kidney disease Liver disease Parkinsons disease, especially in combination with caffeine (may accelerate progression of disease) Pregnant or breastfeeding A pharmacy technician should refer to the pharmacist if the patient 14,16 Has a disease state or condition listed above Asks for a recommendation on which creatine supplement to use Has questions or concerns regarding possible drug interactions or adverse effects Has specific questions about dosing based on their condition, disease state, or current medications or use of other supplements Common Misconceptions People share a considerable amount of information about dietary supplements like creatine online and on other platforms, but some of this information can be inaccurate or misleading

Once retatrutide is approved, expect a similar program to launch within 6 to 12 months

"In general, it's a good idea to work with a dermatologist from the beginning when starting GLP-1 inhibitors, both from an aesthetic and medical perspective, as some expected changes can be more easily prevented or treated with early intervention," Son says

Cardiovasc Diabetol 19 , 115 (2020)