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10.1007/s11160-005-7846-4 42 MechlaouiM.DominguezD.RobainaL.GeraertP
Discovery and development of exenatide: The first antidiabetic agent to leverage the multiple benefits of the incretin hormone, GLP-1
Abstract Many local and systemic diseases especially diseases that are leading causes of death globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart disease and stroke, cancer and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 19 (COVID-19), involve both, (1) oxidative stress with excessive production of reactive oxygen species (ROS) that lower glutathione (GSH) levels, and (2) inflammation
Conclusion We found evidence for the role of lower GSH in patients with MDD in the occipital region of the brain, a difference which is not found in other brain regions or in combined brain region studies
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