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Clinically they vary from being almost flat to being raised by up to a centimetre

Equally important is the urgent need to design societal health responses able to better identify, prevent and manage the disease (WHO 2023)

Inhibition of PPAR leads to serum acylcarnitine accumulation [190], whereas hepatic PPAR activation induced by energy deprivation or fibrates is associated with an increase in the carnitine concentration and a decrease in serum acylcarnitine accumulation [191, 192]