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He says, It can tell other cells that there is fuel available and you can burn that fuel, or it can tell other cells there isnt fuel available. That is somewhat true, however what he cannot reconcile with evidence is it is the opposite relationship to what it should be based on in the CIM
The answer is short and simple: We dont know
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But the potential for the very high efficacy of an injectable to be achievable via a pill represents an important path going forwardit could help markedly reduce the cost and uptake
HIV-1 Tat-mediated microglial activation by impairing mitophagy/autophagy Mitophagy selectively removes damaged mitochondria through a progression from phagophore to autophagosome and then to lysosome, thereby preserving organelle integrity and cellular homeostasis [82]
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