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CD9 depletion synergized with ASCT2 inhibition to suppress PDAC organoid growth and prolong survival in KPC mice, highlighting the therapeutic potential of targeting the CD9ASCT2 axis

Keep liquid extracts as directed on the label, and keep all supplements out of the reach of children

Zeits fr Physiol Chem

Here, we provide the first evidence of improved healthspan and age-related survival with a therapeutic mAb by demonstrating that treatment with an IGF-1R antagonist in older mice significantly and preferentially improves several indices of healthspan, reduced death from neoplastic disease, and increased mean and median lifespan in females

Triterpenoids CDDO and CDDO-Me down-regulate FLIP expression and sensitize AML cells to TRAIL-induced apoptosis