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Abrupt discontinuation often leads to rapid weight regain as appetite returns to baseline or even overshoots temporarily
Canada allows research import under Health Canada's Research Application process but requires advance submission 3060 days before transport
10,11,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,345,346 Currently, drugs targeting BCAA uptake-dependent amino acid transporter LAT1 and metabolic enzymes BCAT and BCKDK are in trials
Acute methionine load-induced hyperhomocysteinemia enhances platelet aggregation, thromboxane biosynthesis and macrophage-derived tissue factor activity in rats
It does not appear to interact negatively with other medications and has been well-tolerated across a wide range of doses in animal models
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