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Aberrant activation of signaling pathways and therapeutic implications Taken together, the aberrant activation of signaling pathways such as PI3K-AKT-mTOR, MAPK, NF-B, TGF-, Wnt/-catenin, JAK/STAT, Notch, Hippo-YAP/TAZ, and GAS6/AXL contributes extensively to therapy resistance across cancer types (Fig
PMID: 26236730 Published Research Highlights Discovery 1973 Tripeptide Identified in Human Serum Pickart and Thaler first identified the GHK sequence in human plasma, discovering a tripeptide that prolonged survival of normal liver cells and stimulated growth in cell culture models
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MaksimovaMYIvanovAVVirusEDNikiforovaKAOchtovaFRSuanovaETet alImpact of glutathione on acute ischemic stroke severity and outcome: possible role of aminothiols redox status