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Dose Escalation Side effects may briefly return but are usually milder
However, some patients report changes in their menstrual cycles, which might indirectly impact planning for pregnancy
The starting dose for Wegovy is 0.25 mg per week, which can be titrated up to the maximum maintenance dose of 7.2 mg per week
Some research suggests altered cortisol dynamics in obesity, including changes in tissue-level cortisol activation in adipose tissue through the enzyme 11-hydroxysteroid dehydrogenase type 1
Importantly, tirzepatide may decrease the effectiveness of oral contraceptives, particularly during dose initiation and escalation
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