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The best non-diabetic body-composition anchor favors tirzepatide, about 75:25 fat-to-lean loss in its DXA data versus about 62:38 in semaglutides. This is cross-trial evidence, not a head-to-head maintenance-dose DXA result

Food Intervention with Folate Reduces TNF- and Interleukin Levels in Overweight and Obese Women with the MTHFR C677T Polymorphism: A Randomized Trial. Nutrients, vol

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While some peptides like GLP-1 (used in prescription medications like Wegovy) are Medsafe approved, many peptides are not and come with serious safety risks because they are not clinically proven or routinely tested

But before diving into a protocol, its crucial to evaluate the potential risks, side effects, and unknowns especially for long-term use