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Lipoic acid also protected liver from oxidative stress-induced liver injury in methotrexate-treated rats through the activation of Nrf-2 pathway and other anti-inflammatory pathways (37)
As the Urano group pointed out, using QuicGSH to monitor the global GSH dynamics requires a bold assumption that the mitochondrial and global GSH are at similar levels
discussion S72-91
Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injury
While neutrophil-derived reactive oxygen species (ROS) play an important role in breaking down damaged fragments of the muscle tissue, ROS produced in excess may also contribute to oxidative stress (for review see [47, 48]
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