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Wegovy In a clinical trial of adults with overweight or obesity (without diabetes), once-weekly semaglutide (Wegovy) led to significantly greater weight loss over 68 weeks compared to once-daily liraglutide (Saxenda)

It can also lower blood pressure and cholesterol levels, reducing the risk of heart disease

Changes in glucagon levels with semaglutide treatment (AUC 512mmol ) were significantly lower compared with placebo (0.87 [0.82, 0.93]

A parallel study by Rosenstock et al