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Factors affecting potassium levels Potassium physiology Approximately 98% of total body potassium is stored intracellularly, while 2% is in serum.[9] In normal kidney function, the kidney is responsible for approximately 90% of potassium excretion, while colonic excretion accounts for approximately 10%.[10] This intra- and extracellular difference in potassium levels is maintained by several complex mechanisms, including sodiumpotassium pumps and hormonal regulation

10.7554/eLife.33006 Elife 103 LiangH.ZhaoH.GleichmanA.MachnickiM.TelangS.TangS.et al (2019)