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Activation of the central melanocortin system chronically reduces body mass without the necessity of long-term caloric restriction

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The Look AHEAD trial observed a 5% reduction in body weight was associated with sustained improvements in key cardiovascular risk factors such as blood pressure and lipid profile [7]

The melanin already synthesised will fade on its natural 34 week timeline as keratinocytes turn over

Some vendors publish lab reports online with batch-specific results accessible via product codes