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doi:10.1016/j.autrev.2025.103864 Zhu H, Zhou L, Wang Q, et al

These advances solved the half-life problem but not the oral delivery problem

Key effects associated with TB-500: Soft tissue repair support Cell migration Angiogenesis Reduced inflammatory signaling Improved tissue remodeling Possible cardiac and neurologic repair effects in preclinical models Like BPC-157, most TB-500 data remains preclinical