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Konig SA, Siemes H, Blaker F, Boenigk E, Gross-Selbeck G, Hanefeld F, Haas N, Kohler B, Koelfen W, Korinthenberg R: Severe hepatotoxicity during valproate therapy: an update and report of eight new fatalities

GLP-1 stands for glucagon-like peptide-1, a hormone naturally released in the intestines after eating

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GLP-1s work through systemic signaling: brain appetite circuits, gut motility, pancreas, liver-facing metabolic changes, and for tirzepatide/retatrutide, additional incretin and glucagon-receptor effects