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Studies have shown that GLP-1 treatment significantly increases the expression levels of BTG2, Pdx1, and the insulin gene in pancreatic cells, indicating that GLP-1 positively regulates insulin gene expression through BTG2, thereby promoting insulin synthesis (Hwang et al., 2013)

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Moreover, resistance continues to increase, largely due to intrinsic defense mechanisms and to the ability of bacteria to transfer antibiotic resistance genes among different species [4, 6]

Remove the needle at the same angle it entered and apply gentle pressure to the site with gauze or a cotton pad