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These transcription factors regulate genes involved in cell cycle progression, extracellular matrix remodeling, and angiogenic signaling
What makes tirzepatide different from earlier medications in this class is that it doesnt just target one hormone pathway, it targets two: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)
[1] These symptoms typically emerge during dose escalation and often improve over time
This could potentially benefit patients with conditions like inflammatory bowel disease, or those with malabsorption syndromes
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