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This research not only provides a comprehensive perspective on the current status and trends of occupational noise-related disease burdens but also offers scientific insights for policymakers and public health managers, advancing the shared goals of global occupational health and health equity
Phosphorylation of IGF-IR/InsR is elevated in ER+ breast cancer cells resistant to estrogen deprivation and tamoxifen, possibly due to increased secretion of IGF1/2 in these cells and elevated expression of retinoblastoma-binding protein 2 that inhibits IGFBP4/5 by interacting with ER-NRIP1-HDAC1 complex [107,108,109]
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Combinatorial targeting of glutamine metabolism and lysosomal-based lipid metabolism effectively suppresses glioblastoma
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