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Loading Phase (Weeks 1-4): 2 to 2.5 mg twice weekly (Monday/Thursday schedule) Maintenance Phase (Weeks 5+): 2 mg once every 7 to 14 days Administration: Subcutaneous injection, location flexible due to systemic distribution Total Cycle: 8 to 12 weeks with 4 to 8 weeks off between cycles The convenience of twice-weekly dosing during loading and weekly or biweekly dosing during maintenance fits easily into Retatrutide schedules

For early-stage thinning, topical may suffice

Looking up or down at the syringe creates parallax error, making the liquid appear higher or lower than it actually is

These side effects generally dissipate within the first few weeks of treatment

Interestingly, as of December 2025, the Wegovy pill offers an oral semaglutide alternative for those who prefer tablets over injections