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(3) ROS induces DNA oxidative damage (such as formation of 8-OHdG) and lipid peroxidation (MDA increase), triggering chondrocyte apoptosis through Bax/Bcl-2 imbalance and activation of caspase-3
For those not breastfeeding, GLP-1 medicines can be effective tools to support weight loss or manage diabetes, but they do come with side effects the most common being nausea, vomiting and diarrhoea
For others, a lower maintenance dose achieves a better quality-of-life balance
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