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The problem with prolonged caloric deficit is that metabolic adaptation your body downregulates energy expenditure over time to resist the deficit
British Journal of Nutrition, 2018
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This activates protein kinase A, which then activates hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides into free fatty acids that can be burned for energy
Start low (50 mg/day), monitor your bodys response, and increase gradually if needed
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