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However, DPRA is not suitable for metallic compounds, because they may form bonds with the nucleophilic residues in histidine 20

This regulatory activity may support endothelial function and promote vessel relaxation, contributing to improved hemodynamic balance in experimental settings

PMID: 16484611 DOI: 10.1161/01.RES.0000214553.37930.3e Fitzgerald DJ, FitzGerald GA (2013): Historical lessons in translational medicine