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Antioxidant enzymes such as superoxide dismutase 1 (SOD1), and glucose6phosphate dehydrogenase (G6PD) decrease from HMRD-induced oxidative stress (OxS) and protein degradation 50,51
In normal conditions, this protein is present in low amounts in the circulation, but upon damage to the intestinal barrier, it is released into the bloodstream (62)
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