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In cancer type 1, when P53 is missing at the genetic level, DINO lnc RNA production, as seen in step 12, remains intact because DINO lncRNA malfunction and p53 gene malfunction cannot exist at the same time (mutually exclusive), since the impact of each malfunction is the same (loss of P53 activity), and the malfunction of both simultaneously is therefore not necessary for the survival of the cancer cell, as seen in Marney et al
Al-Lawati JA, Mohammed AJ, Al-Hinai HQ, Jousilahti P
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