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It is important to note that liver function tests (LFTs) can be normal in NAFLD
PloS Genet (2011) 7(6):e1001393
The total treatment duration to reach maximum dose is similar, around 16 to 20 weeks, but the milligram numbers are an order of magnitude apart
By the time brenipatide is on shelves for weight, tirzepatide will have eight years of real-world data, deeper insurance coverage, and almost certainly other dual or triple agonists in the same competitive space (retatrutide is the obvious next one to land)
it reflects your body finding a new equilibrium at a lower weight
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