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Other rare side effects that have been noted with these drugs include allergic reactions, gallstones (which can occur with a large amount of weight loss), and potential of medullary thyroid cancer (so far only documented in rats, not people), which is why they are contraindicated in people with Type 2 multiple endocrine neoplasia syndrome
Furthermore, as it does not directly suppress appetite, its efficacy as monotherapy may be limited in obesity driven by hedonic overconsumption [26]
[1] [5] This gradual titration approach minimises gastrointestinal adverse effects , which are the most common side effects associated with tirzepatide and other incretin-based therapies
Dual Agonists (Tirzepatide) The Contenders: A Closer Look Comparison: Tirzepatide vs Ozempic vs Victoza Side Effects: What Are the Risks
Dulaglutide-based alternative Dulaglutide is another GLP-1 receptor agonist with similar effects to Zepbound
