Joint discomfort: Elevated GH can cause joint stiffness, achiness, or mild pain
Growth Factor Expression Upregulates TGF-b, FGF, and EGF growth factors that stimulate cell proliferation, collagen synthesis, and extracellular matrix remodeling to rebuild damaged tissue
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The goal is tolerability, not weight loss
At six months, people taking bupropion were 15-20% less likely to gain a clinically significant amount of weight (5% or more of their baseline) than those taking sertraline, the most commonly prescribed antidepressant.1 Some bupropion users actually lost a small amount, about half a pound on average at six months, though this reversed to a modest 1.2-pound gain by 24 months