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Weight loss results were consistently superior to placebo and to comparator medications including semaglutide

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Crucially, the GH response tends to plateau near ~100 mcg per dose , so larger single doses add little extra GH while increasing side effects [12]

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The article highlights that Semaglutide monotherapy provides statistically significant and clinically meaningful weight loss, with the majority of patients experiencing a reduction of 5% or more of their body weight