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Introduction: Two Dominant Anabolic Research Pathways Skeletal muscle hypertrophy research is anchored around two primary mechanistic axes: the IGF-1/IGF-1R-PI3K-Akt-mTORC1 signalling cascade driving protein synthesis, and the myostatin-ActRIIB-SMAD2/3 pathway governing muscle mass ceiling (the brake on hypertrophic growth)

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In-depth interviews were conducted with various primary respondents, including key industry participants, subject-matter experts (SMEs), C-level executives of key market players, and industry consultants, to obtain and verify critical qualitative and quantitative information and assess the growth prospects of the market

(2011) 96:E118896

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