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It stimulates pulsatile GH release, leading to downstream IGF-1 production, and is most commonly discussed in combination with CJC-1295

The peptide is structurally derived from native human GLP-1(7-37) with two amino acid substitutions (Aib at position 8 for DPP-IV resistance, Arg substitution at position 34) and a C18 fatty diacid moiety conjugated via a Glu-(AEEA) linker enabling reversible albumin binding and an extended pharmacokinetic profile compatible with once-weekly dosing

Pramodh, S

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