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As the prevalence of T2DM increases globally and is recognized as a reemerging risk and challenge to manage TB, more research should investigate the possible benefits of using L-GSH as a potential adjunct therapy alongside current anti-TB treatments or even as a preventative strategy for individuals with T2DM with known dysregulation of GSH metabolism and increased oxidative stress
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Microbial metabolism proceeds through a biphasic process: bacterial glycosidases initially catalyze deglycosylation to liberate aglycones, followed by ring-fission and reduction reactions generating diverse phenolic acids and derivatives (243)
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