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In further experiments, systemic injections of relatively high doses (125 g) of thymulin or of an analogue peptide (PAT) deprived of hyperalgesic effect, have been shown to reduce the inflammatory pain and the upregulated levels of cytokines induced by endotoxin (ET) injection

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10.1016/S1470-2045(06)70695-7 16

Treat the decline claim as a plausible hypothesis that has been asserted far more often than it has been measured

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