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A large cohort study in The Lancet Diabetes & Endocrinology found that the diabetes risk a White adult faces at a BMI of 30 shows up in South Asian adults at a BMI as low as 23.9

From a clinical perspective, using frozen-then-thawed semaglutide poses two primary risks

Applying ice for 5 minutes after injection can reduce bruising tendencies, though avoid ice immediately before injection as cold skin reduces medication absorption

Keep it in your carry-on luggage, never in checked bags where cargo hold temperatures can fluctuate dramatically

The addressable patient expansion is estimated to grow the anti-obesity medication market by 180 million new prescription patients between 2027 and 2032