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Pernicious anaemia is caused by a deficiency in vitamin B12, due to atrophic gastritis, an autoimmune condition where the immune system destroys self, in this case the parietal cells of the stomach

After ingestion, stomach acid separates B12 from food proteins, and then intrinsic factor produced in the stomach lining binds to B12 so it can be absorbed in the ileum (the final section of the small intestine)

Prescription requires licensed clinician approval if deemed medically appropriate