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The histidine imidazole nitrogen, the glycine -amino group, and the glycine carbonyl oxygen coordinate to the Cu ion in a square-planar geometry, creating a stable chelate with a dissociation constant in the femtomolar range
Anecdotal reports and limited studies indicate positive effects in inflammation, improving gut health, accelerating healing of tendons and ligaments, and mitigating symptoms of gastrointestinal disorders
Possible Side Effects / Considerations Insomnia, restlessness/anxiety, or fatigue can occur if dose increases too quickly (titration helps)
Monoacylglycerol lipase: a novel potential therapeutic target and prognostic indicator for hepatocellular carcinoma
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