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Among LOX inhibitors, Zileuton (A-64077), a LOX-5 inhibitor, reduces oxidative stress by regulating ROS levels in retinal pigment epithelial (RPE) cells, offering potential for retinal disease treatment (Liu et al., 2015
43 Indeed, this may explain the potent metabolic effects of tirzepatide when pitted against a GLP-1 agonist alone
M.StrazielleN.Ghersi-EgeaJ.-F
Generation of L-cells in mouse and human small intestine organoids
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