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Phosphodiesterase-5 (PDE5) inhibitors remain the first-line pharmacological treatment for ED according to NICE guidance
Besides the biochemical importance of ONOO in living systems, newly confirmed in plant cells, HNO react with thiol-containing proteins/peptides (Arasimowicz-Jelonek et al
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This enhances metabolic pathways such as the tricarboxylic acid cycle and fatty acid biosynthesis, ultimately supporting tumor growth
Gastrointestinal issues, such as nausea, vomiting, diarrhea, and constipation, are among the most frequently reported
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