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2.1.1.2 Subcortical structures Subcortical structures, including the amygdala, hypothalamus, and thalamus, integrate emotional and sensory information with autonomic and neuroendocrine responses to maintain cardiovascular homeostasis ( The Amygdala, a paired limbic structure in the medial temporal lobe, mediates the relationship between psychological stress and CV disease by processing emotional and environmental stimuli ( The Hypothalamus is located at the base of the diencephalon, flanking the third ventricle