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Lack of hydration can also cause or worsen kidney problems
The semaglutide side effects users reported most often in clinical trials were: Nausea Diarrhea Vomiting Constipation Abdominal pain Headache Fatigue More than 20% of trial participants reported these side effects, with 44% reporting nausea and 30% reporting diarrhea compared to 24% or fewer for vomiting, constipation, and abdominal pain
For pure anti-aging goals improved sleep, skin quality, cognitive clarity, and overall vitality sermorelin is often the better starting point
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