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Consequently, only 1015% of GLP-1 reaches circulation intact, leading to fasting plasma levels of only 015 pmol/L
doi: 10.1007/s11695-012-0621-4 73 BeglingerSMeyer-GerspachACGrafSZumstegUDreweJBeglingerCet al
Current sources also support uncertainty around approval timing, real-world availability, long-term uptake, and side-effect tolerance
Esposito, G
Thus, reduced secretion or impaired action of these hormones compromises -cell compensation in response to postprandial glucose stimulation [348]
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