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Furthermore, as with any significant weight loss, adaptive thermogenesis (metabolic adaptation) occurs, whereby the body reduces energy expenditure in response to weight reduction, which would likely counteract any minor metabolic effects
This antibody was later reformulated for nebulization (IN-006) and showed no serious adverse events in phase I trials 79,80
doi: 10.1016/j.jff.2021.104812 175
Clinical variability of autosomal dominant cataract, microcornea and corneal opacity and novel mutation in the alpha A crystallin gene (CRYAA)
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