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Additionally, each year, a cohort with new-onset type 2 diabetes is added (ESM Methodsdiabetes incidence)
According to American Gastroenterological Association guidelines, osmotic laxatives like polyethylene glycol (PEG 3350) are recommended as first-line treatment for tirzepatide-induced constipation, as they are generally safe for regular use and effectively draw water into the colon to soften stools
For patients continuing GLP-1 therapy under a new prescription, options like Ozempic or Mounjaro are sometimes discussed as alternatives depending on individual treatment goals, though any change in medication should be guided by a prescribing physician
The difference for people with and without diabetes suggests that the reasons patients stop treatment may be complex and influenced by multiple factors
Enzymes in the bloodstream chew it up in a matter of minutes
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