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In the duodenum, pancreatic enzymes cleave B12 from R-proteins, allowing binding to intrinsic factor produced by gastric parietal cells
These insights may provide context for personalizing wellness strategies, though the test does not predict exact supplement response
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But for the person looking to support skin health, hair growth, collagen production, and overall tissue health over the long term, sublingual delivery is the more effective choice both because of its strong systemic absorption and because its the format people can actually stick with day after day
& Gibson, I
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